By Christo Christov,Tatyana Karabencheva-Christova
Both concepts for research (computational and experimental) in structural and mechanistic Enzymology have built to some degree independently. although, during the last few years a development has emerged for strengthening their integration. this mixture not just brings jointly computations and experiments fascinated with an analogous enzymatic difficulties, but in addition offers complementary insights into the investigated homes and has a robust synergy impression. This thematic quantity of Advances in Protein Chemistry and Structural Biology makes a speciality of the hot good fortune in structural and mechanistic enzymology and has its major emphasis on explaining the enzyme phenomena by utilizing either the experimental and computational methods. the chosen contributions display how the appliance of a number of experimental strategies and modeling tools is helping extra the certainty of enzyme dynamics, mechanism, inhibition, and drug design.
- Focuses at the contemporary good fortune in structural and mechanistic enzymology
- Has its major emphasis on explaining the enzyme phenomena through the use of either the experimental and computational approaches
- Demonstrates how the applying of quite a few experimental options and modeling equipment is helping extra the certainty of enzyme dynamics, mechanism, inhibition, and drug design
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