By Philip Bittihn
This award-winning thesis investigates the mechanisms underlying cardiac arrhythmia improvement and termination from a wholly new standpoint. via viewing the guts as a posh procedure, the writer makes use of theoretical instruments from nonlinear dynamics mixed with numerical simulations and experiments to accomplish insights into the connection among its constitution and dynamics, thereby paving the way in which in the direction of cutting edge low-energy defibrillation innovations. The paintings tackles, between different issues: the impact of substrate heterogeneity at the spatial-temporal dynamics of cardiac arrhythmias and ways that vulnerable pulsed electrical fields can be utilized to manage those dynamics in heterogeneous cardiac tissue. The long term imaginative and prescient of this examine is to switch the present technique of making use of painful and infrequently tissue harmful electrical surprise – at the moment the single trustworthy strategy to terminate life-threatening traumatic inflammation – through a extra refined yet both powerful intervention. The e-book maps out a few promising examine instructions for biophysicists and scientific researchers engaged on the origins and therapy of cardiac arrhythmias.
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